Effects of methadone, alone or in combination with acepromazine or xylazine, on sedation and physiologic values in dogs.

@article{Monteiro2008EffectsOM,
  title={Effects of methadone, alone or in combination with acepromazine or xylazine, on sedation and physiologic values in dogs.},
  author={Eduardo Raposo Monteiro and Christian Figueroa and Jeison C Choma and Daniela Campagnol and Carlos Mais Bettini},
  journal={Veterinary anaesthesia and analgesia},
  year={2008},
  volume={35 6},
  pages={519-27}
}
OBJECTIVE To evaluate the effects of methadone, administered alone or in combination with acepromazine or xylazine, on sedation and on physiologic values in dogs. STUDY DESIGN Randomized cross-over design. ANIMALS Six adult healthy mixed-breed dogs weighing 13.5 +/- 4.9 kg. METHODS Dogs were injected intramuscularly with physiologic saline (Control), or methadone (0.5mg kg(-1)) or acepromazine (0.1 mg kg(-1)) or xylazine (1.0 mg kg(-1)), or acepromazine (0.05 mg kg(-1)) plus methadone (0… CONTINUE READING