Effects of metformin and ethinyl estradiol-cyproterone acetate on lipid levels in obese and non-obese women with polycystic ovary syndrome.

@article{Rautio2005EffectsOM,
  title={Effects of metformin and ethinyl estradiol-cyproterone acetate on lipid levels in obese and non-obese women with polycystic ovary syndrome.},
  author={Katrina Rautio and Juha S Tapanainen and Aimo O Ruokonen and Laure C Morin-Papunen},
  journal={European journal of endocrinology},
  year={2005},
  volume={152 2},
  pages={269-75}
}
OBJECTIVE Women with polycystic ovary syndrome (PCOS) exhibit risk factors for cardiovascular diseases such as abdominal obesity, insulin resistance and dyslipidemia. Insulin sensitizers, especially metformin, have been shown to improve these metabolic disturbances, but there are only a few studies on their effects on serum lipids in polycystic ovary syndrome. METHODS Thirty-five women with PCOS (18 obese and 17 non-obese) were randomized to 6-month treatments with metformin or ethinyl… CONTINUE READING
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