Effects of metabolic rate on protein evolution.

@article{Gillooly2007EffectsOM,
  title={Effects of metabolic rate on protein evolution.},
  author={James F Gillooly and Michael W. McCoy and Andrew P. Allen},
  journal={Biology letters},
  year={2007},
  volume={3 6},
  pages={655-9}
}
Since the modern evolutionary synthesis was first proposed early in the twentieth century, attention has focused on assessing the relative contribution of mutation versus natural selection on protein evolution. Here we test a model that yields general quantitative predictions on rates of protein evolution by combining principles of individual energetics with Kimura's neutral theory. The model successfully predicts much of the heterogeneity in rates of protein evolution for diverse eukaryotes (i… CONTINUE READING
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