Effects of metabolic and pharmacologic interventions on myocardial infarct size following coronary occlusion.

@article{Maroko1976EffectsOM,
  title={Effects of metabolic and pharmacologic interventions on myocardial infarct size following coronary occlusion.},
  author={Peter R. Maroko and Eugene Braunwald},
  journal={Acta medica Scandinavica. Supplementum},
  year={1976},
  volume={587},
  pages={125-36}
}
A number of hemodynamic, pharmacologic and metabolic interventions were found to change the extent of acute ischemic injury of the myocardium and subsequent necrosis following experimental coronary artery occlusion. Reduction in myocardial damage occurred by decreasing myocardial oxygen demands (beta-adrenergic blocking agents, intra-aortic balloon counterpulsation, external counterpulsation, nitroglycerin, decreasing afterload in hypertensive patients, inhibition of lipolysis, and digitalis in… CONTINUE READING

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