Effects of mercuric chloride on renal plasma membrane function after depletion or elevation of renal glutathione.

@article{Ansari1991EffectsOM,
  title={Effects of mercuric chloride on renal plasma membrane function after depletion or elevation of renal glutathione.},
  author={Rashid Ashid Ansari and R S Thakran and William O. Berndt},
  journal={Toxicology and applied pharmacology},
  year={1991},
  volume={111 2},
  pages={364-72}
}
The role of renal nonprotein sulfhydryls (NPSH) in mercuric chloride-induced nephrotoxicity has been studied in various laboratories. Similarly, the importance of NPSH for mercuric ion accumulation by renal tissue also has been studied. In this study the potential role of NPSH was examined with respect to mercuric ion effects on membrane transport utilizing isolated membrane vesicles prepared from Sprague-Dawley rat kidneys. Sodium gradient-driven p-aminohippurate (PAH) transport in basolateral… CONTINUE READING