Effects of menstrual cycle phase on cocaine self-administration in rhesus macaques.

@article{Cooper2013EffectsOM,
  title={Effects of menstrual cycle phase on cocaine self-administration in rhesus macaques.},
  author={Ziva D Cooper and Richard W. Foltin and Suzette M. Evans},
  journal={Hormones and behavior},
  year={2013},
  volume={63 1},
  pages={105-13}
}
Epidemiological findings suggest that men and women vary in their pattern of cocaine use resulting in differences in cocaine dependence and relapse rates. Preclinical laboratory studies have demonstrated that female rodents are indeed more sensitive to cocaine's reinforcing effects than males, with estrous cycle stage as a key determinant of this effect. The current study sought to extend these findings to normally cycling female rhesus macaques, a species that shares a nearly identical… CONTINUE READING