Effects of melatonin on the oxidative stress induced by thyrotoxicosis in rats.


High concentrations of thyroid hormones can affect the metabolism of oxygen in aerobic conditions and stimulate free radicals generation in mitochondria. Reactive oxygen species are toxic to biomembranes and lead to peroxidation of lipids unless they are not removed by free radical scavengers. A few years ago melatonin (MEL), a pineal hormone, was described… (More)


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