Effects of melatonin and zinc on lipid profile and renal function in type 2 diabetic patients poorly controlled with metformin.

@article{Kadhim2006EffectsOM,
  title={Effects of melatonin and zinc on lipid profile and renal function in type 2 diabetic patients poorly controlled with metformin.},
  author={Haitham Mahmood Kadhim and Sajida Hussein Ismail and Khalid Ibrahim Hussein and Ihsan Hikmat Bakir and Ahmed Salih Sahib and Ban Hoshi Khalaf and Saad A Hussain},
  journal={Journal of pineal research},
  year={2006},
  volume={41 2},
  pages={189-93}
}
Glycemic control and prevention of secondary complications are the most important goals of using pharmacologic treatment of diabetes mellitus (DM). The inadequate responses to oral hypoglycemic agents may be attributed to inadequate postreceptor events even when insulin levels are quite sufficient, and associated with oxidative stress induced by long-term hyperglycemia. The administration of antioxidants such as melatonin and zinc may improve tissue responses to insulin and increase the… CONTINUE READING
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