Effects of medetomidine and xylazine on intraocular pressure and pupil size in healthy Beagle dogs.

@article{Kanda2015EffectsOM,
  title={Effects of medetomidine and xylazine on intraocular pressure and pupil size in healthy Beagle dogs.},
  author={Teppei Kanda and Ayano Iguchi and Chieko Yoshioka and Haruka Nomura and Kanako Higashi and Minami Kaya and Rie Yamamoto and Tomoko Kuramoto and Toshinori Furukawa},
  journal={Veterinary anaesthesia and analgesia},
  year={2015},
  volume={42 6},
  pages={623-8}
}
OBJECTIVE To determine the effects of intramuscular (IM) administration of medetomidine and xylazine on intraocular pressure (IOP) and pupil size in normal dogs. STUDY DESIGN Prospective, randomized, experimental, crossover trial. ANIMALS Five healthy, purpose-bred Beagle dogs. METHODS Each dog was administered 11 IM injections of, respectively: physiological saline; medetomidine at doses of 5, 10, 20, 40 and 80 μg kg(-1), and xylazine at doses of 0.5, 1.0, 2.0, 4.0 and 8.0 mg kg(-1… CONTINUE READING