Effects of maternal oral administration of monosodium glutamate at a late stage of pregnancy on developing mouse fetal brain.

@article{Yu1997EffectsOM,
  title={Effects of maternal oral administration of monosodium glutamate at a late stage of pregnancy on developing mouse fetal brain.},
  author={Tianwei Yu and Yu-Nan Zhao and Wei Shi and Raghavendra Ma and Lissa Yu},
  journal={Brain research},
  year={1997},
  volume={747 2},
  pages={195-206}
}
Monosodium glutamate (MSG) was shown to penetrate placental barrier and to distribute to embryonic tissues using [3H]glutamic acid ([3H]Glu) as a tracer. However, the distribution is not even; the uptake of MSG in the fetal brain was twice as great as that in the maternal brain in Kunming mice. Other maternal mice were given per os MSG (2.5 mg/g or 4.0 mg/g body weight) at 17-21 days of pregnancy, and their offspring behaviors studied. The results showed that maternal oral administration of MSG… CONTINUE READING
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