Effects of maternal exposure to thiamazole on behavioral development in infant cynomolgus monkeys.

Abstract

Thiamazole, an anti-hyperthyroidism agent, was administered orally to pregnant cynomolgus monkeys at doses of 2.0 and 3.5 mg/kg per day from GD 120 to GD 150 to investigate effects on behavioral development of their infants. Swelling of the throat region due to enlargement of the thyroid glands was observed at birth in thiamazole-treated infants, and it… (More)
DOI: 10.1111/cga.12024

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