Effects of maternal dietary supplementation with selenite on the postnatal development of rat offspring exposed to methyl mercury in utero.

@article{Fredriksson1993EffectsOM,
  title={Effects of maternal dietary supplementation with selenite on the postnatal development of rat offspring exposed to methyl mercury in utero.},
  author={Anders Fredriksson and A T G{\aa}rdlund and Kerstin Bergman and Agneta Oskarsson and Bo Ohlin and B R Danielsson and Trevor Archer},
  journal={Pharmacology & toxicology},
  year={1993},
  volume={72 6},
  pages={377-82}
}
Female Sprague-Dawley rats were fed a control standard diet or a selenite (Se) supplemented diet (1.3 p.p.m. Se) for 8 weeks before mating and during gestation and lactation. Blood glutathione peroxidase activity (GSH-Px) was measured as a biomarker of Se in dames. After mating, the females from two dietary groups were divided into three subgroups (6 groups with 10 animals in each) given 0 (vehicle), 2 or 6 mg/kg methyl mercury (MeHg) by gavage on days 6-9 of gestation. Day 2 post parturition… CONTINUE READING
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