Effects of massive small bowel resection on metabolism of bile acids and vitamin D3 and gastrin release in dogs.

@article{Imamura1992EffectsOM,
  title={Effects of massive small bowel resection on metabolism of bile acids and vitamin D3 and gastrin release in dogs.},
  author={Mikio Imamura and Hidemi Yamauchi},
  journal={The Tohoku journal of experimental medicine},
  year={1992},
  volume={168 3},
  pages={515-28}
}
The effects of ursodeoxycholic acid (UDCA) and 1 alpha-hydroxyvitamin D3 on pathophysiological changes following massive resection of the distal small bowel (75%) were investigated by using adult beagle dogs. After surgery, body weight decreased, watery diarrhea occurred, and the transit time of the alimentary tract shortened. These undesirable consequences lessened markedly after oral administration of UDCA, though 1 alpha-hydroxyvitamin D3 was not effective. Plasma levels of both 25… CONTINUE READING