BACKGROUND Manual resistance training (MRT) is a low cost and practically applicable alternative form of resistance training that is ideal for weight rooms with limited equipment. The aim of this study was to compare the acute and subacute hemodynamic responses between MRT and free weight resistance training (FWRT) in normotensive (NT) and hypertensive (HT) men. METHODS Twenty-six untrained men performed a single bout of MRT and FWRT with a minimum 72-hour rest in between. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MBP) were measured, and double product (DP) was calculated. Variables were assessed at different time points: SBP, DBP and MBP (pre- and 15, 30, 45 and 60 minutes postexercise); DP (half-time and postintervention). RESULTS The blood pressure values (BP) were greater in HT men in all analyses and interventions. BP responses were similar between MRT and FWRT in both groups of men. In HT men, there was postexercise hypotension (PEH) after 15, 30 and 60 minutes in MBP measured for both interventions. The DP was greater for the MRT intervention, but within the cardiovascular safety limits. CONCLUSIONS MRT induces PEH in similar levels to FWRT in HT men. Therefore, MRT is a viable and safe alternative for application of FWRT in NT and HT men, reducing the need for expensive equipment.