Effects of mammalian CYP3A inducers on CYP3A-related enzyme activities in grass carp (Ctenopharyngodon idellus): Possible implications for the establishment of a fish CYP3A induction model.

Abstract

Unexpected drug-drug interactions in fish are generally associated with the induction of CYP3A activity and may lead to the formation of drug residues and thus threaten the safety of fishery products. However, little information is available about CYP3A induction in fish. In the present study, we determined the in vivo and in vitro effects of typical… (More)

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@article{Li2008EffectsOM, title={Effects of mammalian CYP3A inducers on CYP3A-related enzyme activities in grass carp (Ctenopharyngodon idellus): Possible implications for the establishment of a fish CYP3A induction model.}, author={Dan Li and Xian-Le Yang and Shu-jun Zhang and Mao Lin and Wen-juan Yu and Kun Hu}, journal={Comparative biochemistry and physiology. Toxicology & pharmacology : CBP}, year={2008}, volume={147 1}, pages={17-29} }