Effects of mace and nutmeg on human cytochrome P450 3A4 and 2C9 activity.

@article{Kimura2010EffectsOM,
  title={Effects of mace and nutmeg on human cytochrome P450 3A4 and 2C9 activity.},
  author={Yuka Kimura and Hideyuki Ito and Tsutomu Hatano},
  journal={Biological & pharmaceutical bulletin},
  year={2010},
  volume={33 12},
  pages={1977-82}
}
Pharmacokinetic or pharmacodynamic interactions between herbal medicines or food constituents and drugs have been studied as crucial factors determining therapeutic efficacy and outcome. Most of these interactions are attributed to inhibition or induction of activity of cytochrome P450 (CYP) metabolic enzymes. Inhibition or induction of CYP enzymes by… CONTINUE READING