Effects of mTOR and calcineurin inhibitors combined therapy in Epstein-Barr virus positive and negative Burkitt lymphoma cells.

@article{Wowro2016EffectsOM,
  title={Effects of mTOR and calcineurin inhibitors combined therapy in Epstein-Barr virus positive and negative Burkitt lymphoma cells.},
  author={Sylvia J. Wowro and Katharina Rose Luise Schmitt and Giang Hai Tong and Felix Berger and Stephan Schubert},
  journal={International immunopharmacology},
  year={2016},
  volume={30},
  pages={9-17}
}
Post-transplant lymphoproliferative disorder is a severe complication in solid organ transplant recipients, which is highly associated with Epstein-Barr virus infection in pediatric patients and occasionally presents as Burkitt- or Burkitt-like lymphoma. The mammalian target of rapamycin (mTOR) pathway has been described as a possible antitumor target whose… CONTINUE READING