Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats.

@article{Besheer2008EffectsOM,
  title={Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats.},
  author={Joyce Besheer and Sara P Faccidomo and Julie J. M. Grondin and Clyde W Hodge},
  journal={Alcohol},
  year={2008},
  volume={42 1},
  pages={13-20}
}
The Group I family of metabotropic glutamate receptors includes subtype 1 (mGlu1) and subtype 5 (mGlu5) receptors. This family of receptors has generated interest as potential targets for different areas of therapeutic development, including intervention for alcohol and drug abuse. Most of this interest is driven by findings showing involvement of mGlu5 receptors in the regulation of drug self-administration; however, studies examining the role of mGlu1 receptors in drug self-administration are… CONTINUE READING

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mGlu1 receptor blockade

  • W. Danysz, A. Y. Bespalov
  • 2007

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