Effects of lycopene supplementation on plasma and tissue lycopene levels in various rodent strains.

Lycopene has been shown to have various biologic effects, and rats and mice are often used for elucidating its in vivo effects and mechanisms. Here, we compared plasma and tissue lycopene levels in F344 rats, BALB/c mice, nude mice, and gerbils by oral supplementation with lycopene (20 mg/kg BW x 2d) every other morning for 10 days. We found that livers… CONTINUE READING