Effects of lowering cerebrospinal fluid pressure on the shape of the peripapillary retina in intracranial hypertension.

@article{Sibony2014EffectsOL,
  title={Effects of lowering cerebrospinal fluid pressure on the shape of the peripapillary retina in intracranial hypertension.},
  author={Patrick A. Sibony and Mark J. Kupersmith and Robert A Honkanen and F. James Rohlf and Ali Torab-Parhiz},
  journal={Investigative ophthalmology & visual science},
  year={2014},
  volume={55 12},
  pages={8223-31}
}
PURPOSE To analyze the deformations of the peripapillary retinal pigment epithelium-basement membrane (ppRPE/BM) layer in response to procedures that lower intracranial pressure (ICP). Second, to demonstrate how shape changes may complement the mean retinal nerve fiber layer (RNFL) thickness as a measure of intracranial hypertension (ICH) and papilledema. METHODS We used geometric morphometrics on spectral-domain optical coherence tomography images to analyze shape change of the ppRPE/BM… CONTINUE READING
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