Effects of low osmolar contrast media on cardiac function: optimal sodium concentration for contractility.


The effects of adding NaCl to the non-ionic contrast medium iohexol (Omnipaque) were investigated in the isolated rat heart. Iohexol (150 mgI/ml) with 0, 10, 20, 30, 50, 145 mM NaCl added and the ionic dimeric compound ioxaglate (Hexabrix 160 mgI/ml) containing approximately 75 mM NaCl were examined. Coronary flow rate (CFR), heart rate (HR), left… (More)


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