Effects of low-dose dopamine on renal and systemic hemodynamics during incremental norepinephrine infusion in healthy volunteers.

@article{Hoogenberg1998EffectsOL,
  title={Effects of low-dose dopamine on renal and systemic hemodynamics during incremental norepinephrine infusion in healthy volunteers.},
  author={Klaas Hoogenberg and Andries J. Smit and Armand R J Girbes},
  journal={Critical care medicine},
  year={1998},
  volume={26 2},
  pages={260-5}
}
OBJECTIVES To assess the effects of low-dose dopamine on norepinephrine-induced renal and systemic vasoconstriction in normotensive healthy subjects. DESIGN On separate days, either a low-dose dopamine (4 microg/kg/min) or a placebo (5% glucose) infusion was added in a single, blinded, randomized order to incremental norepinephrine infusions of 40, 80, and 150 ng/kg/min over a 60-min period each. SETTING Outpatient clinic of a university-affiliated hospital. SUBJECTS Normotensive healthy… CONTINUE READING

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