Effects of low‐level light therapy on hepatic antioxidant defense in acute and chronic diabetic rats

@article{Lim2009EffectsOL,
  title={Effects of low‐level light therapy on hepatic antioxidant defense in acute and chronic diabetic rats},
  author={Jinhwan Lim and Zeeshan M. Ali and Ruth A. Sanders and Ann C. Snyder and Janis T. Eells and Diane S. Henshel and John Bernald Watkins},
  journal={Journal of Biochemical and Molecular Toxicology},
  year={2009},
  volume={23}
}
Diabetes causes oxidative stress in the liver and other tissues prone to complications. Photobiomodulation by near infrared light (670 nm) has been shown to accelerate diabetic wound healing, improve recovery from oxidative injury in the kidney, and attenuate degeneration in retina and optic nerve. The present study tested the hypothesis that 670 nm photobiomodulation, a low‐level light therapy, would attenuate oxidative stress and enhance the antioxidant protection system in the liver of a… 
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Effect of Photomodulation Therapy on Development of Oxidative Stress in Blood Leukocytes of Rats with Streptozocin-Induced Diabetes Mellitus
TLDR
It is shown that the PBMT increased superoxide dismutase (SOD) activity in rats with DM and normalized the content of oxidative stress markers (thiobarbituric acid-active products, oxidatively modified proteins, and protein glycation end products).
Light-emitting diode therapy reduces persistent inflammatory pain: Role of interleukin 10 and antioxidant enzymes
Photobiomodulation Mitigates Diabetes-Induced Retinopathy by Direct and Indirect Mechanisms: Evidence from Intervention Studies in Pigmented Mice
TLDR
PBM is a novel non-pharmacologic treatment strategy to inhibit early changes of diabetic retinopathy and induces retinal protection against abnormalities induced by diabetes in pigmented animals, and even as an intervention.
Morin alleviates fructose-induced metabolic syndrome in rats via ameliorating oxidative stress, inflammatory and fibrotic markers
TLDR
It is revealed that morin has an exquisite effect against metabolic disorders in the experimental model through, at least in part, antioxidant, anti-inflammatory, and anti-fibrotic mechanisms.
Phototherapy improves wound healing in rats subjected to high-fat diet
TLDR
The results showed phototherapy accelerated the cutaneous wound healing by modulating oxidative stress in rats with metabolic disorders under a high-fat diet.
Effect of LED photobiomodulation on fluorescent light induced changes in cellular ATPases and Cytochrome c oxidase activity in Wistar rat
TLDR
LED light preexposure showed a significant enhancement in the degree of increase in the enzyme activities in almost all the tissues and at all the time points assessed in most of the tissues.
Low-intensity far-red light inhibits early lesions that contribute to diabetic retinopathy: in vivo and in vitro.
TLDR
PBM ameliorated lesions of diabetic retinopathy in vivo and reduced oxidative stress and cell death in vitro and is concluded that PBM is a simple adjunct therapy to attenuate the development of diabetic Retinopathy.
Low-level laser therapy (LLLT) reduces oxidative stress in primary cortical neurons in vitro.
TLDR
Although LLLT increases ROS in normal neurons, it reduces ROS in oxidatively-stressed neurons and in both cases MMP is increased, which may explain how L LLT can reduce clinical oxidative stress in various lesions while increasing ROS in cells in vitro.
Age-related retinal inflammation is reduced by 670 nm light via increased mitochondrial membrane potential
Inhibitory modulation of cytochrome c oxidase activity with specific near-infrared light wavelengths attenuates brain ischemia/reperfusion injury
TLDR
The data suggest that COX-inhibitory NIR may be a viable non-pharmacologic and noninvasive therapy for the treatment of cerebral reperfusion injury.
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References

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