Effects of losartan on myocardial ischemia reperfusion injury in rats

@inproceedings{Yongping2005EffectsOL,
  title={Effects of losartan on myocardial ischemia reperfusion injury in rats},
  author={Zheng Yong-ping},
  year={2005}
}
AIM: To explore the effect of angiotensin II type 1 receptor antagonist losartan on the myocardial infarct size,the ultrastructure of myocardium,the production of tumor necrosis factor-α(TNF-α) and interleukin-6(IL-6) ,and to investigate the possible molecular protective mechanism of losartan on myocardial ischemia reperfusion(I/R) injury in rats. METHODS: Forty-two healthy male SD rats were divided into four groups:(1)Control group(n=6);(2)Ischemia reperfusion group(I/R group,n=12):the left… CONTINUE READING

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