Effects of long-term rifampicin administration in primary biliary cirrhosis.

  title={Effects of long-term rifampicin administration in primary biliary cirrhosis.},
  author={L Bachs and Albert Pares and Monserrat Elena and Carlos Piera and J. J. Rodes},
  volume={102 6},
The effects of rifampicin treatment (10 mg.kg-1.day-1) on pruritus and cholestasis were evaluated in 16 patients with primary biliary cirrhosis and pruritus followed up for 2-24 months. Assessment of pruritus severity, liver tests, aminopyrine breath test, and bile acids was done at 2 weeks and every 3 months after the beginning of the study. Two patients (12.5%) were withdrawn after 2 months of treatment because they had hepatitis caused by rifampicin. Four patients were withdrawn after 4… CONTINUE READING
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