Effects of long-term combined treatment with somatostatin analogues and pegvisomant on cardiac structure and performance in acromegaly

@article{Auriemma2016EffectsOL,
  title={Effects of long-term combined treatment with somatostatin analogues and pegvisomant on cardiac structure and performance in acromegaly},
  author={Renata Simona Auriemma and Ludovica Francesca Stella Grasso and Mariano Galdiero and Maurizio Galderisi and Claudia Pivonello and Chiara Simeoli and Maria De Martino and Rosario Ferrigno and Mariarosaria Negri and Cristina de Angelis and Rosario Pivonello and Annamaria Colao},
  journal={Endocrine},
  year={2016},
  volume={55},
  pages={872-884}
}
To date, no data are available on the effects of long-term combined treatment with somatostatin analogues (SA) and pegvisomant (PEG) on cardiovascular complications in acromegaly. The current study aimed at investigating the effects of long-term SA + PEG on cardiac structure and performance. Thirty-six patients (14 M, 22 F, aged 52.3 ± 10.2 years) entered this study. Weight, BMI, systolic (SBP) and diastolic (DBP) blood pressure, IGF-I, fasting glucose (FG), fasting insulin (FI), HOMA-IR, HbA1c… CONTINUE READING

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