Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial

@article{Pearce2014EffectsOL,
  title={Effects of long-term blood pressure lowering and dual antiplatelet treatment on cognitive function in patients with recent lacunar stroke: a secondary analysis from the SPS3 randomised trial},
  author={Lesly A. Pearce and Leslie A. McClure and David C. Anderson and Claudia Jacova and for the SPS3 Investigators},
  journal={The Lancet Neurology},
  year={2014},
  volume={13},
  pages={1177-1185}
}
BACKGROUND The primary outcome results for the SPS3 trial suggested that a lower systolic target blood pressure (<130 mm Hg) might be beneficial for reducing the risk of recurrent stroke compared with a higher target (130-149 mm Hg), but that the addition of clopidogrel to aspirin was not beneficial compared with aspirin plus placebo. In this prespecified secondary outcome analysis of the SPS3 trial, we aimed to assess whether blood pressure reduction and dual antiplatelet treatment affect… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Clinical features and racial / ethnic diff erences among the 3020 participants in the Secondary Prevention of Small Subcortical Strokes ( SPS 3 ) trial

  • EL Teng, K Hasegawa, A Homma
  • J Stroke Cerebrovasc Dis
  • 2013

Long - term eff ects of secondary prevention on cognitive function in stroke patients

  • N Mavaddat, A Roalfe, K Fletcher
  • Circulation
  • 2013

ects of secondary prevention on cognitive function in stroke patients

  • N Mavaddat, A Roalfe, K Fletcher
  • Circulation
  • 2013

Eff ects of clopidogrel added to aspirin in patients with recent lacunar stroke

  • OR Benavente, CL White, L Pearce
  • N Engl J Med
  • 2012

Similar Papers

Loading similar papers…