• DOI:10.2460/JAVMA.2002.221.654
Corpus ID: 11617609

Effects of long-term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation.

@article{Atkins2002EffectsOL,
  title={Effects of long-term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation.},
  author={C. Atkins and W. Brown and J. R. Coats and M. Crawford and T. DeFrancesco and J. Edwards and P. Fox and B. Keene and L. Lehmkuhl and Michael Luethy and K. Meurs and Jean-Paul Petrie and F. Pipers and S. Rosenthal and J. Sidley and J. Straus},
  journal={Journal of the American Veterinary Medical Association},
  year={2002},
  volume={221 5},
  pages={
          654-8
        }
}

C. Atkins, W. Brown, +13 authors J. Straus

Published 2002

Medicine

Journal of the American Veterinary Medical Association

OBJECTIVE To determine the effect of long-term administration of enalapril on renal function in dogs with severe, compensated mitral regurgitation. DESIGN Randomized controlled trial. ANIMALS 139 dogs with mitral regurgitation but without overt signs of heart failure. PROCEDURE Dogs were randomly assigned to be treated with enalapril (0.5 mg/kg [0.23 mg/lb], PO, q 24 h) or placebo, and serum creatinine and urea nitrogen concentrations were measured at regular intervals for up to 26 months… CONTINUE READING

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