Effects of long-lasting sulpiride therapy on growth hormone secretion in mentally disturbed children.

Abstract

The effects of chronic sulpiride therapy on growth hormone (GH) secretion were studied in 11 mentally disturbed children, aged 5 to 13 years, five with personality disorders, three with childhood psychoses, one with hysteria, one with anxiety reactions, and one with neurosis. The basal GH secretion and response to insulin-induced hypoglycemia were studied before the beginning of therapy and after ten days and three months of treatment with sulpiride (8 mg/kg body weight). No modifications in basal levels of GH or in the response to the stimulus were observed after ten days of therapy. After three months of treatment a blunted GH response to the stimulation was observed in three subjects, one of whom showed increased basal levels of GH.

Cite this paper

@article{Brambilla1981EffectsOL, title={Effects of long-lasting sulpiride therapy on growth hormone secretion in mentally disturbed children.}, author={Francesca Brambilla and A Guareschi-Cazzullo and Claudio Musetti and Laura Musetti and Paula Nobile}, journal={Clinical therapeutics}, year={1981}, volume={4 2}, pages={95-102} }