Effects of local anesthetics on properties of tetrodotoxin-sensitive protein reconstituted into liposomes

Abstract

The effects of some local anesthetics on properties of tetrodotoxin (TTX)-sensitive protein reconstituted into liposomes in such a manner that its TTX-sensitive center is located at the internal surface of the liposome membrane were studied. It was shown that tetracaine, lidocaine and its derivative QX-314 decreased the rate of efflux of radioactive sodium… (More)
DOI: 10.1007/BF01053339

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