Effects of levcromakalim and nucleoside diphosphates on glibenclamide-sensitive K+ channels in pig urethral myocytes.

@article{Teramoto1997EffectsOL,
  title={Effects of levcromakalim and nucleoside diphosphates on glibenclamide-sensitive K+ channels in pig urethral myocytes.},
  author={Noriyoshi Teramoto and Gordon McMurray and Alison Frances Brading},
  journal={British journal of pharmacology},
  year={1997},
  volume={120 7},
  pages={1229-40}
}
1. Effects of levcromakalim and nucleoside diphosphates (NDPs) on both membrane currents and unitary currents in pig proximal urethra were investigated by use of patch clamp techniques (conventional whole-cell configuration, nystatin perforated patch, cell-attached configuration and inside-out patches). 2. Levcromakalim produced a concentration-dependent outward current at a holding potential of -50 mV. The peak current amplitude showed little variation when measured by either conventional… CONTINUE READING