Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-d-aspartate antagonists

@article{Wolf1995EffectsOL,
  title={Effects of lesions of prefrontal cortex, amygdala, or fornix on behavioral sensitization to amphetamine: Comparison with N-methyl-d-aspartate antagonists},
  author={Marina E. Wolf and Susan L. Dahlin and X. -T. Hu and C J Xue and Kathryn S. White},
  journal={Neuroscience},
  year={1995},
  volume={69},
  pages={417-439}
}
Behavioral sensitization to amphetamine involves the mesoaccumbens dopamine system and is accompanied by cellular changes in this system. Excitatory amino acid antagonists, when co-administered with amphetamine, prevent both behavioral sensitization and associated changes in the mesoaccumbens dopamine system. This suggests that excitatory amino acid-dependent events are critical to the initiation of sensitization. This study sought to identify excitatory amino acid projections required for… Expand
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Ibotenic acid lesions of prefrontal cortex do not prevent expression of behavioral sensitization to amphetamine
We have shown previously that ibotenic acid lesions of the prefrontal cortex, performed prior to repeated amphetamine administration, do not affect sensitization of stereotyped behaviors but doExpand
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