Effects of leptin on secretion of LH and FSH from primary cultured female rat pituitary cells.

@article{Ogura2001EffectsOL,
  title={Effects of leptin on secretion of LH and FSH from primary cultured female rat pituitary cells.},
  author={Koji Ogura and Minoru Irahara and Machiko Kiyokawa and Michiko Tezuka and Toshiya Matsuzaki and Toshiyuki Yasui and Masaharu Kamada and Toshihiro Aono},
  journal={European journal of endocrinology},
  year={2001},
  volume={144 6},
  pages={653-8}
}
BACKGROUND Leptin, which is the product of the obese gene, is believed to play important roles in pubertal development and reproductive function in females. In a study using adult male rats, it was found that leptin stimulated secretion of gonadotropin from the pituitary in a dose-related manner. However, there has been no such study in female rats. OBJECTIVE To investigate the effects of leptin on the production of LH and FSH from the pituitary in female rats, using primary cultured… CONTINUE READING
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