Effects of left ventricular hypertrophy on force and Ca2+ handling in isolated rat myocardium.

Abstract

To study the effect of left ventricular (LV) hypertrophy on force and Ca2+handling in isolated rat myocardium, LV hypertrophy was induced in rats by banding of the abdominal aorta. After 16 wk, arterial pressure was assessed by catheterization. LV trabeculae were isolated and loaded with indo 1 salt by iontophoretic injection. Isometric force and… (More)
DOI: 10.1152/ajpheart.1998.274.4.H1361

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