Effects of latrunculin-B on outflow facility and trabecular meshwork structure in human eyes.

@article{Ethier2006EffectsOL,
  title={Effects of latrunculin-B on outflow facility and trabecular meshwork structure in human eyes.},
  author={C. Ross Ethier and A. Thomas Read and Darren W-H Chan},
  journal={Investigative ophthalmology & visual science},
  year={2006},
  volume={47 5},
  pages={1991-8}
}
PURPOSE To determine the effect of the F-actin-disrupting agent latrunculin-B on aqueous outflow facility and trabecular meshwork architecture in human eyes. METHODS After baseline facility measurement in human eye bank eyes (n = 9 pairs), one eye of each pair received anterior chamber exchange and continued perfusion with medium containing 1 microM latrunculin-B. Contralateral eyes were treated in a similar manner with vehicle. Eyes were fixed by anterior chamber exchange and perfusion with… CONTINUE READING
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