Effects of lactulose and other laxatives on ileal and colonic pH as measured by a radiotelemetry device.

@article{Bown1974EffectsOL,
  title={Effects of lactulose and other laxatives on ileal and colonic pH as measured by a radiotelemetry device.},
  author={Rodney L. Bown and John A. Gibson and Gordon E. Sladen and Brent J. Hicks and Alberta M. Dawson},
  journal={Gut},
  year={1974},
  volume={15 12},
  pages={
          999-1004
        }
}
Using a pH-sensitive radiotelemetering device the effect of lactulose on luminal pH in the ileum, colon, and rectum has been compared with that of two other laxative agents. Lactulose produced marked acidification of proximal colonic contents but this effect was not consistently maintained into the distal colon. Sodium sulphate acidified distal rather than proximal colonic contents. However, for a similar degree of laxation it was not possible to produce a significantly more uniform reduction… CONTINUE READING

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Accurate localization of a fall in pH within the ileocecal region: validation using a dual-scintigraphic technique.

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