Effects of lacidipine on peak oxygen consumption, neurohormones and invasive haemodynamics in patients with mild to moderate chronic heart failure.


OBJECTIVE To evaluate the efficacy and safety of the second generation dihydropyridine calcium channel blocker lacidipine in patients with heart failure. DESIGN Placebo controlled, parallel group, double blind study over 8 weeks. SETTING General community hospital in Breda, The Netherlands. PATIENTS A random sample was studied of 25 outpatients with… (More)


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