Effects of kiwi fruit consumption on platelet aggregation and plasma lipids in healthy human volunteers

  title={Effects of kiwi fruit consumption on platelet aggregation and plasma lipids in healthy human volunteers},
  author={Asim K. Duttaroy and Audun J{\o}rgensen},
  pages={287 - 292}
Fruits and vegetables have been thought to be beneficial in cardiovascular disease. [] Key Result We report that consuming two or three kiwi fruit per day for 28 days reduced platelet aggregation response to collagen and ADP by 18% compared with the controls (P < 0.05). In addition, consumption of kiwi fruit lowered blood triglycerides levels by 15% compared with control (P < 0.05), whereas no such effects were observed in the case of cholesterol levels. All these data indicate that consuming kiwi fruit may…
Cardioprotective properties of kiwifruit.
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    Advances in food and nutrition research
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The influence of diet and nutrients on platelet function.
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Repeat testing of platelet function may be required, not only afterclusion of known antiplatelet medications but also potentially after exclusion of dietary substances/nutrients that could have plausibly affected initial test data.
Role of dietary polyphenols in platelet aggregation. A review of the supplementation studies
The observed inhibitory effect of polyphenols on platelet aggregation might explain, at least in part, the epidemiological data on beneficial effect of dietary polyphenol intake from diet on cardiovascular disease risk and suggests a role forpolyphenols in helping to prevent cardiovascular diseases.
Tomato extract, commercially known as Fruitflow,  is an absolutely unique dietary solution for cardiovascular support that works immediately after ingestion by helping to keep blood platelets smooth, thereby promoting healthy circulation and pressure within the cardiovascular system.
Effects of kiwifruit consumption on serum lipid profiles and antioxidative status in hyperlipidemic subjects
Regular consumption of kiwifruit might exert beneficial effects on the antioxidative status and the risk factors for CVD in hyperlipidemic subjects.
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Some foods such as lemon, leek, garlic, scallion, ginger, tomato and grapefruit showed good anti-platelet aggregation effect similar or higher than that of positive control group i.e. aspirin (ASP), which provides scientific reference for reasonable selection of daily dietary with supplementary curative effects or prevention of cardiovascular diseases (CVD).
Inhibitory effects of kiwifruit extract on human platelet aggregation and plasma angiotensin-converting enzyme activity
The effects of kiwifruit extract on human blood platelet aggregation and plasma angiotensin-converting enzyme (ACE) activity are investigated and it is indicated that kiw ifruit contains very potent antiplatelet and anti-ACE components.
Kiwifruit decreases blood pressure and whole-blood platelet aggregation in male smokers
It is suggested that intake of kiwifruit may have beneficial effects on BP and platelet aggregation in male smokers.
Effects of kiwi consumption on plasma lipids, fibrinogen and insulin resistance in the context of a normal diet
Consumption of at least one kiwi/week is associated with lower plasma concentrations of fibrinogen and improved plasma lipid profile in the context of a normal diet and regular exercise.


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The hydroxycinnamates and the flavonoid quercetin inhibited platelet function, although not at levels that can be achieved in human plasma by dietary intervention, and polyphenols inhibit platelet aggregation at levels lower than those previously reported.
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Experimental dietary studies in humans showed the capacity of vegetables and fruit and their constituents to modulate some of these potential disease-preventive mechanisms, including modulation of detoxification enzymes, stimulation of the immune system, and reduction of platelet aggregation.
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The results suggest that resveratrol can inhibit platelet aggregation both in vitro and in vivo, which conceivably could be one of the mechanisms by which this red wine polyphenol exerts its cardioprotective effects.
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Increased consumption of fruit and vegetables can increase the plasma antioxidant capacity in humans, as measured as oxygen radical absorbance capacity (ORAC), and alpha-tocopherol concentrations.
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Pure ethanol has been shown to inhibit platelet aggregation in vitro, ex vivo, and in vivo, although a blood alcohol content (BAC) of > or = 0.2 g/dL is usually required, much less than is usually necessary for platelet inhibition with pure ethanol.