Effects of kainic acid on body temperature of rats: Role of catecholaminergic and serotonergic systems

@article{Turski1980EffectsOK,
  title={Effects of kainic acid on body temperature of rats: Role of catecholaminergic and serotonergic systems},
  author={Lechosław Turski and Zdzisław Kleinrok},
  journal={Psychopharmacology},
  year={1980},
  volume={71},
  pages={35-39}
}
Intraventricular (IV) administration of doses of 0.1 μg kainic acid caused diphasic effects on the body temperature of rats — initially hypothermia, rapidly followed by hyperthermia. Pretreatment of rats with 6-OHDA effectively blocked the hypothermic and significantly increased the hyperthermic effects of kainic acid. The hyperthermic effect of kainic acid was reversed in the 5,6-DHT- and dorsal raphe-lesioned rats. However, the electrolytic lesion of the medial raphe nucleus did not cause any… CONTINUE READING

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