Effects of isoproterenol on the metabolism of normal and ischemic heart.


A study has been made of the simultaneous evolution of cardiac activity and metabolism in the dog heart in situ, during the perfusion of isoproterenol in a dose comparable to therapeutic doses (1 micrograms x kg-1 x min-1, 30 min). A total cardiopulmonary by-pass system allowed of taking the repeated myocardial tissue samples necessary for the determination… (More)


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