Effects of isoflurane anesthesia on local cerebral glucose utilization in the rat.

@article{Ori1986EffectsOI,
  title={Effects of isoflurane anesthesia on local cerebral glucose utilization in the rat.},
  author={C Ori and Mauro Dam and Gilberto Pizzolato and Leontino Battistin and Gildardo Gir{\'o}n},
  journal={Anesthesiology},
  year={1986},
  volume={65 2},
  pages={152-6}
}
The effect of isoflurane anesthesia on local rate of glucose utilization was investigated in the rat brain by means of the autoradiographic 14C-2-deoxyglucose method. Local cerebral glucose utilization (LCGU) was measured in 26 neuroanatomic structures of awake and isoflurane-anesthetized rats. Isoflurane anesthesia (1.5% inspired) caused both increases and decreases in LCGU. Significant reductions were found in all cortical areas examined and in primary sensory relay nuclei of central visual… CONTINUE READING

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