Effects of isoflurane, sevoflurane, and halothane on myofilament Ca2+ sensitivity and sarcoplasmic reticulum Ca2+ release in rat ventricular myocytes.

@article{Davies2000EffectsOI,
  title={Effects of isoflurane, sevoflurane, and halothane on myofilament Ca2+ sensitivity and sarcoplasmic reticulum Ca2+ release in rat ventricular myocytes.},
  author={Lucy A Davies and Carly E Gibson and Mark R. Boyett and Philip M Hopkins and Simon M. Harrison},
  journal={Anesthesiology},
  year={2000},
  volume={93 4},
  pages={1034-44}
}
BACKGROUND The aim of this study was to describe and compare the effects of isoflurane, sevoflurane, and halothane at selected concentrations (i.e., concentrations that led to equivalent depression of the electrically evoked Ca2+ transient) on myofilament Ca2+ sensitivity, sarcoplasmic reticulum (SR) Ca2+ content, and the fraction of SR Ca2+ released during… CONTINUE READING