Effects of iron oxide nanoparticles on cardiac differentiation of embryonic stem cells.

@article{Au2009EffectsOI,
  title={Effects of iron oxide nanoparticles on cardiac differentiation of embryonic stem cells.},
  author={K K Au and Song-Yan Liao and Yee-ki Lee and Wing-Hon Kevin Lai and K KP Ng and Yau-chi Chan and Mei-Chu Yip and Chung-Yee Jenny Ho and Ed Xuekui Wu and Ronald A. Li and Chung-wah Siu and Hung-fat Tse},
  journal={Biochemical and biophysical research communications},
  year={2009},
  volume={379 4},
  pages={898-903}
}
The therapeutic potential of transplantation of embryonic stem cells (ESCs) in animal model of myocardial infarction has been consistently demonstrated. The development of superparamagnetic iron oxide (SPIO) nanoparticles labeling and cardiac magnetic resonance imaging (MRI) have been increasingly used to track the migration of transplanted cells in vivo allowing cell fate determination. However, the impact of SPIO- labeling on cell phenotype and cardiac differentiation capacity of ESCs remains… CONTINUE READING