Effects of iron deficiency and iron overload on angiogenesis and oxidative stress-a potential dual role for iron in breast cancer.

@article{Jian2011EffectsOI,
  title={Effects of iron deficiency and iron overload on angiogenesis and oxidative stress-a potential dual role for iron in breast cancer.},
  author={Jinlong Jian and Qing Yang and Jisen Dai and Jonathan Eckard and Deborah Axelrod and Julia Smith and Xi Huang},
  journal={Free radical biology & medicine},
  year={2011},
  volume={50 7},
  pages={841-7}
}
Estrogen alone cannot explain the differences in breast cancer (BC) recurrence and incidence rates in pre- and postmenopausal women. In this study, we have tested a hypothesis that, in addition to estrogen, both iron deficiency due to menstruation and iron accumulation as a result of menstrual stop play important roles in menopause-related BC outcomes. We… CONTINUE READING