Effects of ionizing radiation on mitochondria.

@article{Kam2013EffectsOI,
  title={Effects of ionizing radiation on mitochondria.},
  author={Winnie Wai-Ying Kam and Richard B. Banati},
  journal={Free radical biology & medicine},
  year={2013},
  volume={65},
  pages={
          607-619
        }
}
The current concept of radiobiology posits that damage to the DNA in the cell nucleus is the primary cause for the detrimental effects of radiation. However, emerging experimental evidence suggests that this theoretical framework is insufficient for describing extranuclear radiation effects, particularly the response of the mitochondria, an important site of extranuclear, coding DNA. Here, we discuss experimental observations of the effects of ionizing radiation on the mitochondria at (1) the… CONTINUE READING
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