Effects of iodine on thyroid status of fetus versus mother in treatment of Graves' disease complicated by pregnancy.

@article{Momotani1992EffectsOI,
  title={Effects of iodine on thyroid status of fetus versus mother in treatment of Graves' disease complicated by pregnancy.},
  author={Naoko Momotani and Tomoko Hisaoka and Jaeduk Yoshimura Noh and Naofumi Ishikawa and Kunihiko Ito},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1992},
  volume={75 3},
  pages={738-44}
}
To investigate the effect of maternal iodine therapy for Graves' disease on fetal thyroid, we examined serum free T4 (FT4) and TSH levels in the fetus vs. those in the mother. Patients who were severely thyrotoxic were not included. Cord and maternal sera were tested at delivery in 35 patients with Graves' disease treated with iodine alone during pregnancy (6-40 mg daily). At the initiation of therapy, the mothers were at 11-37 weeks gestation, and FT4 levels ranged from 28.3-65.8 pmol/L. At… CONTINUE READING