Effects of intraventricular angiotensin II mediated by the sympathetic nervous system.

@article{Falcn1978EffectsOI,
  title={Effects of intraventricular angiotensin II mediated by the sympathetic nervous system.},
  author={Jacky Falc{\'o}n and Michael Ian Phillips and William E. Hoffman and Michael J. Brody},
  journal={The American journal of physiology},
  year={1978},
  volume={235 4},
  pages={H392-9}
}
Central effects of angiotensin II were studied in rats treated with adrenalectomy, chemical sympathectomy with intravenous 6-hydroxydopamine, or a combination of both. Unrestrained, unanesthetized rats were compared before and after one of the three treatments to determine water drinking and blood pressure responses to intracerebroventricular (ivt) injections of 50 and 500 ng angiotensin II (AII). Adrenalectomy alone did not alter either drinking or pressor response to AIIivt. Peripheral… CONTINUE READING