Corpus ID: 43734554

Effects of intravenous anaesthetics on nerve axons.

  title={Effects of intravenous anaesthetics on nerve axons.},
  author={Evelyne Benoit},
  journal={European journal of anaesthesiology},
  volume={12 1},
  • E. Benoit
  • Published 1995
  • Medicine
  • European journal of anaesthesiology
The effects of ketamine, etomidate, alphaxalone and alphadolone acetate on nodal sodium and potassium currents of frog myelinated nerve fibre have been examined. The four general anaesthetics reversibly depressed ionic currents, although they tended to be more effective in blocking potassium than sodium current. The potassium current was reduced by etomidate and alphaxalone in a time-dependent manner. This was not found for ketamine and alphadolone acetate. In addition to blocking effects on… Expand
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