Effects of intracoronary verapamil administration in a sheep model of acute myocardial ischemia and reperfusion.

@article{Korn1988EffectsOI,
  title={Effects of intracoronary verapamil administration in a sheep model of acute myocardial ischemia and reperfusion.},
  author={Robert L. Korn and Jennifer Pollock and J A Spath},
  journal={Circulation research},
  year={1988},
  volume={62 6},
  pages={1138-46}
}
We evaluated the efficacy of intracoronary administration of verapamil hydrochloride in reducing myocardial injury during acute ischemia and reperfusion. Ischemia was induced by 30% and 45% reductions of circumflex arterial blood flow for successive 2-hour periods. A reperfusion period (1 hour and 45 minutes) followed ischemia upon deflation of a pneumatic… CONTINUE READING