Effects of intraaccumbens administration of SCH-23390 on cocaine-induced locomotion and conditioned place preference.

@article{Baker1998EffectsOI,
  title={Effects of intraaccumbens administration of SCH-23390 on cocaine-induced locomotion and conditioned place preference.},
  author={D. A. Baker and Rita A. Fuchs and Sheila E. Specio and Taline V. Khroyan and Janet L. Neisewander},
  journal={Synapse},
  year={1998},
  volume={30 2},
  pages={181-93}
}
The effects of systemic (0-1.0 mg/kg) or intraaccumbens (0-1.0 microg/side) administration of SCH-23390 on cocaine-induced (0 or 4.2 mg/kg, i.v.) locomotion, sniffing, and conditioned place preference (CPP) were investigated in rats. After behavioral testing was completed, animals were injected with their respective dose of SCH-23390 into the nucleus accumbens (NAc), followed by a systemic injection of the irreversible antagonist N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ). Receptors… CONTINUE READING

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